Caleb Appleton

Caleb enjoys partnering with teams to build and execute against ambitious visions to use technology to reshape the physical world. A biomedical engineer by training, Caleb’s career spans early science work in the field of engineered gene and cell therapies, frontier tech investing and most recently operating a scaled technology business. At Bison,he’s focused on techbio and AI in the physical world investments including Vivodyne, Passkey and Cobot.

Prior to investing at Bison, Caleb was an investor at Innovation Endeavors, where he focused on frontier technology investments across surgical robotics (RBOT), drug discovery(Eikon Therapeutics, Dewpoint Therapeutics), next generation hardware (Skylo),and applied AI (SQ4.0, Citrine Informatics). Caleb spent the last two years ata growth-stage portfolio company, TuneIn, as Senior Vice President and GM leading a $50M P&L. Caleb began his career at Bain & Company.

When not investing,Caleb can reliably be found on two wheels out-pedaling the San Francisco fog.He is also way too particular about his coffee: roasting his own beans and constantly tinkering with his latte art.

Caleb has a B.S. degree in Biomedical Engineering from Georgia Tech and Emory and currently serves on the External Advisory Board for the Biomedical Engineering Department at Georgia Tech and Emory.